Pheochromocytoma and functional paraganglioma.

PURPOSE

Pheochromocytomas and paragangliomas are rare tumors of chromaffin cell origin. Their identification is likely increasing owing to the increased use of radiographic images detecting incidental adrenal masses.

RECENT FINDINGS

The pathophysiology of hypertension induced by the release of catecholamines and newly discovered peptides has been shown to be more complex than the concept of episodic catecholamine release.

SUMMARY

This review looks at the most recent advances in the physiology and molecular basis of these tumors.