Oncogenic SF3B1 mutations alter the splicing of mRNA noncoding regions to induce a novel therapeutic vulnerability.

Sekrecki M, Sekrecka A, Lattupally RR, Le K, Jin X, Mozes C, Dwyer BG, Zhuang Z, Romero BA, Pineda JMB, Cao X, Nguyen L, Chen VW, Zhou C, Wallace JA, Tanaka KL, Tiwari C, Gabel A, Kim WJ, Stanley RF, Benbarche S, Thind J, Muruganandham A, Zhang TYY, Greenberg PL, Gotlib J, Mannis GN, Shomali W, Salmasi GG, Kuo CJ, Shanafelt TD, Singh I, Inoue D, Hansen FK, Gray NS, Van Rechem C, Fakhri B, Zhang X, Lu SX