University of California San Francisco
UCSF School of Medicine UCSF Medical Center

Craniofacial team management in Apert syndrome.

American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
2012
https://researcherprofiles.org/profile/1160604
22449603
Oberoi S, Hoffman WY, Vargervik K
Abstract

INTRODUCTION

Apert syndrome is one of the rarest of the craniosynostosis syndromes. Affected persons have extensive structural and functional impairments, some of which can be life threatening. Management requires team care from infancy to adulthood. The purposes of this article are to assess the outcomes in individuals with Apert syndrome after completion of treatment and to review current protocols for craniofacial team care and dental, orthodontic, and orthognathic surgical management.

METHODS

This was a retrospective cohort study of 8 subjects with Apert syndrome. Cephalograms at 2 time points were compared: adolescence (before midface advancement) and at least 1 year after advancement. The cephalometric values were compared with paired t tests. Team protocols are delineated.

RESULTS

Measurements indicating forward positioning of the maxilla increased significantly: SNA by 10.7° (P = 0.002) and midface length by 9.6 mm (P = 0.002). Sagittal jaw relationship improved significantly as well: ANB by 14° (P = 0.004) and the Wits appraisal by 8 mm (P = 0.003). Vertical dimensions also increased.

CONCLUSIONS

All individuals had significantly improved and stable positions of the midface and normalized facial profiles after treatment.

Journal Issue
Volume 141 of Issue 4 Suppl