Skip to main content
University of California San Francisco
UCSF School of Medicine UCSF Medical Center
Home
  • Facebook
  • Twitter
  • Youtube

Mega Menu

  • About Us
    • Our Mission
    • Our People
    • Our Impact
      • Annual Reports
      • Bridges Newsletter
      • Medical Education Podcast
      • News
    • Advancing, Diversity, Equity, and Inclusion
    • Job Opportunities
    • Program Statistics
    • Guidelines & Policies
    • Educational Support Resources
      • Technology Enhanced Education
      • Anatomy Learning Center
      • Willed Body Program
      • Kanbar Center for Simulation and Clinical Skills
    • LCME Accreditation
    • ACGME Accreditation Program
    • ACCME Accreditation Program

    lab

    UCSF is an institution of higher learning where tomorrow’s leaders in the life sciences, health care and health policy receive high-quality education and training. By recruiting the top faculty members, students, residents, and staff nationwide, UCSF — a community of the best and the brightest — sustains its reputation for excellence in education, discovery, and clinical care.

     

    UCSF Medical Education Overview

  • MD Program
    • Prospective Students
      • Admissions/MD Programs
      • Applying to Medical School
      • Post Baccalaureate Program
      • Outreach Programs
      • Bridges Curriculum
    • Education Programs
    • Current Students
      • School of Medicine Deans
      • Medical Student Guidelines & Policies
      • Student Services
      • Bridges Curriculum
      • Student Experience Team
      • Tools
      • Visiting Student Program
      • Advising and Career Development

    prospective students

    At UCSF, our learners approach health care challenges with critical thinking and a spirit of inquiry. As tomorrow's health and science leaders in training, UCSF students embody our passion for advancing the health of our communities.

     

    MD Program Overview

  • Residents & Fellows
    • Resident & Clinical Fellows Resources
    • Program Administration Resources
    • GME Calendar and Events
    • About UCSF Training Programs
    • About the office of GME
    • GME Educational & Professional Development Opportunities
    • Well-Being and Mental Health Resources for Residents and Clinical Fellows

    continuing students having a discussion standing in front of their Posters

    Our learners train across the specialties in leading national accredited and non-accredited programs, across the specialties; graduates are enrolled in interdepartmental degree programs in basic and translational sciences, social and population sciences and clinical sciences.

     

    Residents & Fellows Overview

  • Faculty Educators
    • Academy of Medical Educators
      • Membership & Application
      • Programs and Collaborations
      • Academy Membership Directory
    • Faculty Development
      • Online Resources for Teaching Faculty
      • Educational Skills Workshops & Med Ed Grand Rounds
      • Teach for UCSF Certificate Program
      • Teaching Scholars Program (TSP)
      • Advanced Education Programs
      • Educational Scholarship Conference (ESCape)
      • Teaching Observation Program
    • Research & Innovation
      • Engaging in Health Professions Education Research
      • Educational Research Faculty
      • Funding Opportunities
    • Our Community
      • Program Outcomes & Success Stories
      • Events
      • Educator's Portfolio
      • CFE News and Announcements
      • Contact Center for Faculty Educators
    • Recognition and Awards
      • Academy Celebration of New Members
      • Distinguished Teaching Awards
    • Volunteer Clinical Professors
      • Teaching Opportunities

    Placeholder photo of faculty

    Upcoming Events:

    • Annual Education Showcase ~ May 16-19
    • Accelerated Path for Teach for UCSF Certificate Program on Sunday, May 22

    ASPIRE UCSF Logo

    Center for FACULTY EDUCATORS OVERVIEW

  • Continuing Education
    • Office of Continuing Medical Education
    • CME Credits
    • Resources for Participants
    • Resources for Presenters

    continuing meded

    Our Office of Continuing Education offers educational opportunities for physicians, nurses, physician assistants, dentists, and health care professionals to improve their practices through a comprehensive selection of continuing education activities.

     

    Continuing Education Overview

Breadcrumb

  1. People
  2. Jacque Duncan, MD

Jacque Duncan, MD

Professor of Clinical Ophth

Retinitis pigmentosa (RP) affects about 1 in 3,500 people worldwide. Age-related macular degeneration (AMD) affects as many as 1 in 4 people by the age of 75 and is the leading cause of blindness in people over age 50 in the United States. Both RP and AMD have a hereditary basis, and currently, there is no cure for either of these types of hereditary retinal degeneration. My clinical specialty is diagnosing and caring for patients with these diseases, using modalities from fluorescein angiography, to optical coherence tomography (OCT), to electroretinography (ERG).

In both RP and AMD, loss of vision is a result of photoreceptor cell degeneration and death. Treatments that can prevent photoreceptor degeneration in experimental models of retinal degenerations may have utility in preventing degeneration in both RP and AMD. I am interested in investigating novel treatments to preserve retinal function in patients with RP, cone rod dystrophy, Stargardt disease, Best disease and AMD.

Patients with rod specific defects undergo degeneration not only of rods, but also of cone photoreceptors. Because cones are responsible for fine visual acuity and color perception, their degeneration is particularly disabling for patients. I am interested in studying the relationship between cone photoreceptor survival and rod-specific gene defects in hereditary retinal degenerations, with the goal of preserving visual function mediated by both rods and cones.

A major challenge in the study of retinal degenerations lies in the fact that the cells affected by these diseases, the photoreceptors and retinal pigment epithelial (RPE) cells, are not visible in the eyes of living people. My collaborator Dr. Austin Roorda at the UC Berkeley School of Optometry has developed a novel device, the adaptive optics scanning laser ophthalmoscope (AOSLO), with the ability to image individual cone photoreceptors in the central retina of living eyes. We have studied cones in patients with RP, cone-rod dystrophy and other types of retinal degeneration to better understand why vision is lost in these diseases. See Dr. Roorda’s laboratory webpage for additional details about this research.

The UCSF Retinal Degenerations Clinic participated in 3 multi-center clinical trials for patients with inherited retinal degenerations. Two Phase II/III clinical trials evaluated the effect that a growth factor called ciliary neurotrophic factor (CNTF) has on retinal function in patients with early and late stages of RP. A Phase I study evaluated the safety and efficacy of a new generation epiretinal prosthetic device to stimulate visual perception in patients with end-stage RP. These clinical trials are among the first to study possible treatments for patients with these blinding diseases.
Education
2018 - Diversity, Equity, and Inclusion Champion Training, University of California
2018 - Sexual Orientation and Gender Identity Training, University of California
Fellowship, Medical Retina and Inherited Retinal Degenerations, 2000 - Center for Hereditary Retinal Degenerations, Scheie Eye Institute, University of Pennsylvania
Ophthalmology Residency, 1999 - Ophthalmology, University of California, San Francisco
Internship, Internal Medicine Preliminary Program, 1996 - School of Medicine, University of California, San Francisco
M.D., 1995 - Medicine, University of California, San Francisco
Jacque Duncan, MD

+1 415 514-4241

 jacque.duncan@ucsf.edu

  • ABOUT US
    • Career Opportunities
    • School of Medicine Guidelines & Policies
    • Educational Support Resources
    • Clery Act Notice of Annual Security and Fire Safety Reports
  • FOR FACULTY EDUCATORS
    • Educational Skills Workshops
    • Faculty Development Resources
  • FOR CURRENT STUDENTS
    • Bridges Curriculum
    • Tools & Resources
  • MD PROGRAM
    • Admissions Office
    • Our Outreach Programs

Footer

  • ABOUT US
    • Career Opportunities
    • School of Medicine Guidelines & Policies
    • Educational Support Resources
    • Clery Act Notice of Annual Security and Fire Safety Reports
  • FOR CURRENT STUDENTS
    • Bridges Curriculum
    • Tools & Resources
  • FOR FACULTY EDUCATORS
    • Educational Skills Workshops
    • Faculty Development Resources
  • MD PROGRAM
    • Admissions Office
    • Our Outreach Programs

UCSF SOM Logo

UCSF Giving

© 2019 The Regents of the University of California. The University of California San Francisco  |  UCSF Medical Center