Molecular Medicine Faculty
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MMP faculty have made a commitment to mentoring MMP Students and Residents, and participating in Molecular Medicine Case Conference. MMP faculty have appointments in many departments across the schools of Medicine, Dentistry, Pharmacy, and the Graduate Division at UCSF, and work in laboratories at Parnassus Heights, Mission Bay, Mount Zion, San Francisco General Hospital, and the Veterans Administration.
Faculty/Email | Title | Research Interests |
| Harold Bernstein, MD, PhD | Professor, Pediatrics and CVRI | cell cycle regulation, stem cell biology, cell signaling, muscle biology, myocardial regeneration, heart failure website
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| Robert Nussbaum, MD | Professor, Medicine and Genetics | Human molecular genetics, Parkinson's disease, Mouse models website
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Professor Chair, Pathology | cell cycle regulation, stem cell biology, cell signaling, muscle biology, myocardial regeneration, heart failure website
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| Nadav Ahituv, PhD | Asst. Professor Biopharmaceutical Science and IHG | human genetics, genomics, gene regulation, limb malformations, obesity, pharmacogenomics, enhancer, mouse models, zebrafis website |
| Mark S. Anderson, MD, PhD | Asst. Professor Diabetes | autoimmunity, immune tolerance, thymic selection website |
| Sergio E. Baranzini, PhD | Adj. Asst. Professor, Neurology Gladstone Institute | systems biology, multiple sclerosis genetics/genomics, gene expression/bioinformatics, experimental neuroimmunology, mathematical/statistical modeling website |
| Diane L. Barber, PhD | Professor and Vice Chair, Cell and Tissue Biology | cell migration, cancer, metastasis, turmorigenesis, actin cytoskeleton, intracellular pH, epithelial to mesenchymal transition (EMT) website |
| Michael S. Beattie, PhD | Professor, Neurological Surgery | neural injury and repair, regeneration, spinal cord injury, apoptosis, stem cell transplantation, recovery of neurological function, cell death, de- and remyelination website |
| Daniel D. Bikle, MD, PhD | Professor, Endocrine | vitamin D and calcium regulation of keratinocyte differentiation; role of IGF-I in the anabolic response of bone to mechanical load and parathyroid hormone website |
| Harold A. Chapman, MD | Professor, Medicine and Pulmonary | interstitial lung disease and pulmonary fibrosis, integrin signaling in lung cancer, epithelial mesenchymal transition pathways of TGFβ1 signaling website |
| Shweta Choudhry, PhD | Asst. Adjunct Professor, Lung Biology | asthma, COPD, interstitial lung diseases, diabetes, cardiovascular disease, metabolic, syndrome, complex diseases, population genetics, molecular genetics, pharmacogenetics, admixture, admixture mapping, population stratification, understudied populations, race/ethnicity, candidate gene, studies, genome-wide association studies, gene-environment interactions, gene-gene interaction, pathway analysis website |
| Céline I. Colnot, Ph.D | Asst. Professor, Orthopaedic Surgery | Cartilage and Bone Biology, Developmental Biology, Skeletal Repair and Regeneration, Cellular and Molecular Biology, Skeletal Stem Cells, In vivo Cell Lineage Analysis, Angiogenesis, Inflammation, Extracellular Matrix Remodeling website |
| Bruce R. Conklin, MD | Sr. Investigator Gladstone Institute of Cardiovascular Disease, Professor, UCSF Department of Medicine, Division of Medical Genetics | Signaling, Hormones, G protein coupled receptors, stem cells, cardiac, bioinformatics website |
| Michael Salvatore Conte, MD | Chief, Vascular Surgery | vascular injury, vein bypass graft, angioplasty, gene therapy, smooth muscle cells website |
| Heike E. Daldrup-Link, MD, PhD | Associate Professor, Radiology and Pediatrics | imaging, molecular imaging, cellular imaging, cell tracking radiology website BMS website
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| Jayanta Debnath, MD | Assistant Professor, Pathology | autophagy, apoptosis, oncogenes, breast cancer, three-dimensional culture, epithelial cancersextracellular matrix, integrins, ubiquitin-like molecules website |
| David Erle, MD | Professor, Medicine | asthma, immunology, genomics, gene regulation, DNA microarrays, micro-RNA website |
| Donna M. Ferriero, MD | Professor, Neurology and Pediatrics | brain development, newborn brain injury, excitotoxicity, hypoxia inducible genes, neuroprotection website |
| Howard L. Fields, MD, PhD | Professor, Neurology and Physiology | alcoholism and drug addiction, neuroscience of motivation website |
| James A. Frank, MD | Associate Professor, Medicine | acute lung injury, acute respiratory distress syndrome, pulmonary edema, ion transport, permeability, tight junction, alveolar epithelium, pulmonary fibrosis, sepsis, lung cancer website |
| Fen-Biao Gao, PhD | Associate Professor, Neurology | frontotemporal dementia, neurodegeneration, microRNAs website |
| Michael S. German, MD | Professor, Diabetes Center | diabetes mellitus, insulin, carbohydrate metabolism, pancreas, islets of Langerhans, beta-cells, developmental, biology, stem cell, biology, regeneration, gene expression, transcription factors, microRNA, genomics website |
| Linda Giudice, MD, PhD, MSc | Professor and Ob/Gyn Chair, Ob/Gyn and Reproductive Sciences | human reproduction, functional genomics, steroid hormone action, endocrine disruptors, mucosal immunity, ovarian cancer, stem, cells, translational science website
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| Su Guo, PhD | Associate Professor, Biopharmaceutical Sciences | neuroscience, developmental biology, stem cells, Parkinson's disease, genetics, dopamine biology, behavior website |
| Nalin Gupta, MD, PhD
| Associate Professor, Neurological Surgery and Pediatrics | pediatric brain tumors, macrophage infiltration, drug delivery, mouse models website
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| Jiang He, PhD | Assistant Professor, Radiology | molecular imaging, drug targeting and drug delivery, nanotechnology, peptide, antibody discovery; radiotracer, radiopharmaceutics, radiotherapy, nuclear imaging; angiogenesis, breast cancer, prostate cancer, pancreatic cancer website |
| Michelle Hermiston, MD, PhD | Asst. Professor, Pediatrics | signal transduction, phosphatase, mouse models of benign and malignant hematologic disease, leukemia, lymphoma, phospho-flow cytometry, macrophage activation syndrome, lupus, autoimmunity, tolerance, dendritic cell, B cell, homeostasis website
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| Katherine M. Hyland, PhD | Associate Professor, Biochemistry and Biophysics | Professional Courses Co-Director website |
| Ajay N. Jain, PhD
| Professor, Cancer Research Institute | molecular docking, molecular similarity, ligand-based activity modeling, organism-scale multi-target prediction of biological activity, and computational approaches to rationalizing pharmacology website |
| Ella Fung Jones, PhD
| Asst. Professor, Radiology | molecular imaging, optical imaging, multi-modality imaging, contrast agents development for X-ray and optical imaging, in vivo monitoring of protease activities, disease progression, drug dosage response, targeted imaging website |
| Ophir David Klein, MD, PhD | Assistant Professor, Orofacial Surgery | stem cells, developmental biology, regenerative medicine, craniofacial biology, bone biology website |
| Scott Kogan, MD | Associate Professor, Laboratory Medicine | leukemia, hematopoiesis, cancer stem cells, carcinogenesis website |
| Arnold R. Kriegstein, MD, PhD | Director, Institute for Regeneration Medicine | cortical development, neural stem cells, neural progenitor cells, neurogenesis, radial glia, neuronal migration, developmental neurobiology, neurophysiology website |
| Deanna L. Kroetz, PhD | Professor, Biopharmaceutical Sciences | pharmacogenetics, drug netabolism, drug transporters, renal cytochrome P450 eicosanoid website |
| Jennifer LaVail, PhD | Professor, Anatomy and Ophthalmology | neurobiology, virology, herpetic infections of the brain, axonal transport website |
| Patricia A. Leake, PhD | Professor, Otolaryngology - Head and Neck Surgery | cochlear implants, auditory system development, plasticity, neurotrophins website |
| Andrew D. Leavitt, MD | Professor, Laboratory Medicine and Medicine Medical Director, Adult Blood and Marrow Transplant Laboratory | human embryonic stem cells, hematopoietic stem cells, thrombopoietin/MPL signaling website |
| Randall J. Lee, MD, PhD | Professor, Cardiology, Section of Electrophysiology | tissue engineering, myocardial regeneration, stem cells, antibodies website |
| Jay A. Levy, MD | Professor, Hematology/Oncology | HIVAIDS, immunology, cell biology website |
| Long-Cheng Li, MD | Assistant Professor, Urology | RNA activation, gene regulation, small RNA and cancer website |
| Daniel A. Lim, MD, PhD | Asst. Professor, Neurosurgery | stem cells, adult neurogenesis, chromatin remodeling, epigenetics, cell transplantation, gene therapy, stereotactic neurosurgery, MRI-guided neurosurgery, neurodegenerative disease, Parkinson's disease, demyelinating diseases website |
| Tippi C. MacKenzie, MD | Asst. Professor of Surgery | stem cell transplantation, tolerance induction, fetal and neonatal immunity, fetal therapy website |
| Sharmila Majumdar, PhD | Professor and Vice Chair, Radiology | radiology, magnetic resonance imaging, image processing,computer-assisted, osteoporosis, osteoarthritis, osteoarthritis, knee, osteoarthritis, hip, imaging, bioengineering, cartilage, bone, inter-vertebral disc, musculoskeletal website |
Asst. Professor, Orthopaedic Surgery | craniofacial development, structural birth defects, Shh, Fgf, Bmp, Wnt, neural crest, skeletal repair, stem cell therapy, trauma website | |
| Marta Margeta, MD, PhD | Asst. Professor, Pathology | Metabolism, Excitability, and Neurologic Disease website |
| Carol Anne Mathews, MD | Assoc. Professor, Psychiatry | genetics, psychopathology, phenomenology, endophenotypes, psychiatric disorders of childhood, genetic epidemiology website |
| Michael A. Matthay, MD | Professor, Medicine and Anesthesia | mesenchymal stem cells, lung fluid balance, acute lung injury, transport of salt, water and protein by the pulmonary epithelium website |
| Martin McMahon, PhD | Professor, Cancer Research Institute | RAF kinases; MAP kinase signaling; mouse models of human cancer; Cell cycle regulation; apoptosis; experimental therapeutics website |
| Michael T. McManus, PhD | Assistant Professor, Diabetes Center | RNA interference, microRNAs, development, genetics, mouse models, noncoding RNAs website |
| Patrick S. McQuillen, MD | Assoc. Professor, Pediatrics Critical Care | developmental neuroscience, early hypoxic ischemic brain injury, selective vulnerability, plasticity, repair, regeneration, visual system, congenital heart disease, magnetic resonance imaging, neurodevelopmental, outcome, neuroprotection website |
| Robert O. Messing, MD | Professor, Neurology | substance abuse, anxiety, pain, neuronal signal transduction, protein, kinase C, GABAA receptor, corticotrophin releasing hormone, neuropeptide Y, voltage-gated calcium channels, gene targeting, RNA interference, electrophysiology, behavioral pharmacology website |
| Theodore Miclau, MD | Professor, Orthopaedic Surgery | fracture, repair, molecular and cellular events, inflammation, angiogenesis, bone, and cartilage website |
| Robert A. Nissenson, PhD | Professor, Medicine and Physiology | control of bone mass by G protein signaling in osteoblasts; molecular determinants of osteoblast differentiation; role of G protein signaling in mesenchymal stem cell fate decisions; interplay between the anabolic effects of parathyroid hormone and canonical Wnt signaling in osteoblasts website |
| Douglas F. Nixon, MD, PhD | Professor, Medicine | HIV, immunity, T cells, endogenous retroelements, HTLV-1, mycobacterium tuberculosis, NK, NKT website |
| Linda J. Noble, PhD | Professor, Neurological Surgery | matrix metalloproteinases, oxidative stress, CNS trauma website |
| Scott Oakes, MD | Assistant Professor, Pathology | biochemistry of apoptosis, BCL-2 family, endoplasmic reticulum stress, myeloma, neurodegenerative disease website
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| Jorge R. Oksenberg, PhD | Professor, Neurology | biochemistry of apoptosis, BCL-2 family, endoplasmic reticulum stress, myeloma, neurodegenerative disease website |
| Joel M. Palefsky, MD | Professor, Laboratory Medicine and Medicine | human papillomavirus, human immunodeficiency virus, Epstein Barr virus, anogenital cancer, anogenital intraepithelial neoplasia website |
| Boris Matija Peterlin, MD | Professor, Medicine, Microbiolology and Immunology | acquired and congenital immunodeficiencies, HIV/AIDS, immunotherapy of cancer, models of autoimmunity: transcription of MHC class II genes, antigen processing and presentation; replication of HIV, latency, mechanism of action of viral accessory genes; control of elongation of transcription in health and disease; global health website |
| Samuel J. Pleasure, MD, PhD | Associate Professor, Neurology | brain development; dentate gyrus; migration; Wnts; chemokines; retinoic, acid; meninges website |
| Louis J. Ptácek, MD | Professor, Neurology | episodic disorders, epilepsy, migraine, circadian rhythm genetics, pathophysiology, animal modeling, human genetics website |
| Jennifer M. Puck, MD | Professor, Immunology | primary immunodeficiency (PID), translational research, mouse models, newborn screening, immunology, genetics, gene therapy, severe combined immunodeficiency (SCID), autoimmune lymphoproliferative, syndrome (ALPS), hyper-IgE syndrome, lymphocyte development website |
| Katherine A. Rauen, MD, PhD | Associate Professor, Pediatrics Genetics | array CGH, cardio-facio-cutaneous syndrome, cancer genomics, cancer syndromes, Costello syndrome, constitutional chromosome aberrations, cytogenetics, congenital abnormalities, genetic medicine, medical education, neurofibromatosis 1, Noonan syndrome, prenatal genetics, Ras/MAPK pathway website |
| Dorit Ron, PhD | Associate Professor, Neurology | molecular neurobiology of addiction, signal transduction website |
| Philip J. Rosenthal, MD | Professor, Infectious Diseases | malaria, Plasmodium, parasitology, drug resistance, Africa, protease website |
| Mark A. Schumacher, MD, PhD | Associate Professor, Anesthesia | TRPV1, VR1, capsaicin receptor, splice variant, NGF, promoter, nociceptor, pain, transcription factors website |
| Kevin S. Shannon, MD | Professor, Pediatrics, Hematology and Oncology | myeloid leukemia, mouse models, Ras, targeted therapeutics website |
| Robin Mark Shaw, MD, PhD
| Assistant Professor, Medicine and Cardiology | cardiac electrophysiology, ion channels, membrane protein,trafficking, congestive heart failure, arrythmia, sudden cardiac, death, microRNA, TIRF microscopy website |
| Dean Sheppard, MD | Professor, Medicine, Lung | molecular bases of common lung diseases, in vivo, biology of integrins website |
| Elliott. H. Sherr, MD, PhD | Assistant Professor, Neurology | autism, epilepsy, cognitive disability, genetics, brain development, diffusion tensor imaging, corpus callosum website |
| Paul C. Simpson, MD | Professor, Cardiology | drug discovery, adrenergic receptors, knockout and transgenic mouse models, human heart tissue bank, heart and vascular cell culture (human, mouse, rat), cardiovascular molecular and cellular biology and physiology, brain ischemia, GPCR signaling, heart disease, heart failure, cardiomyopathy, heart transplantion, Neurological disease, traumatic brain injury website |
| Anne Slavotinek, MD, PhD | Associate Professor, Clinical Pediatrics Genetics | birth defects, malformations, multiple congenital anomaly syndromes, congenital diaphragmatic hernia, anophthalmia, genome sequencing, microarrays, in-situ hybridization, expression studies, morpholino studies website |
| Matthew L. Springer, PhD | Associate Professor, Cardiology | angiogenesis, cardiac function, endothelial function, bone marrow cell therapy, gene therapy, endothelial progenitor cells, flavanols, second hand cigarette smoke website |
| Deepak Srivastava, MD | Director, Gladstone Institute Cardiovascular Disease | microRNA, cardiac development, differentiation website |
| Didier Y. R. Stainier, PhD | Professor, Biochemistry | vertebrate organ formation/cardiovascular development/endoderm, liver, pancreas and gut development and regeneration/stem cell differentiation/lipid transport and metabolism website |
| Raymond A. Swanson, MD | Professor, Neurology | neuroscience, inflammation, mitochondria, oxidative stress, stroke, Parkinson's disease, DNA damage website |
| Christian Vaisse, MD. PhD | Associate Professor, Diabetes Research Center | obesity, diabetes, human genetics, neural regulation of energy homeostasis, hypothalamus website |
| Zinaida S. Vexler, PhD | Associate Professor, Neurology | stroke, neurodegeneration, inflammation, chemokine, protection, repair, neonate, MRI website |
| Thiennu H. Vu, MD, PhD
| Associate Professor, Lung Biology Center | lung development, lung vascular development, lung alveolar development, asthma, lung cancer, COPD, respiratory diseases, global health website |
| Zena Werb, PhD | Professor, Anatomy | breast development, breast cancer, epithelial biology, tumor, microenvironment, tumor metastasis website |
| Paul J. Wolters, MD | Assistant Professor, Pulmonary and Critical Care | mast cell, sepsis, pneumonia, IL-6, protease, fibrosis, matrix, remodeling, epithelial to mesenchymal transition, translational, research, Th2 cytokine website |
| Anthony Wynshaw-Boris, MD, PhD | Division Chief, Pediatrics Medical Genetics | mouse models of human neurogenetic disease, neuronal migration defects, neurogenesis, neural tube closure, social behavior, autism website |
| Keith R. Yamamoto, PhD | Professor, Cellular and Molecular Pharmacology | mouse models of human neurogenetic disease, neuronal migration defects, neurogenesis, neural tube closure, social behavior, autism website |
| Yerem Yeghiazarians, MD | Assistant Professor, Medicine | stem cell (adult and embryonic), myocardial infarction, myocardial repair, vascular biology, basic, translational and clinical research website |
| Midori Yenari, MD | Associate Professor, Neurology | stroke, cerebral ischemia, inflammation, microglia, stress proteins website |
| William L. Young, PhD | Professor, Anesthesia, Neurosurgery and Neurology | neuroanesthesia, intracranial hemorrhage, brain arteriovenous malformations, intracranial aneurysm, cerebral hemodynamics website |